Research Award Details

2018 - Zimmer Biomet Spine Research Grant

Determination of the Incidence & Nature of Lumbosacropelvic Deformity in Presumed Idiopathic Scoliosis Using a Novel Technique of MR Sequence & Workstation 3D Reconstruction


Grant Recipient: John Birch, MD

Institution:
TSRH, Dallas
Presentations & Publications:

Presentations:
Goldberg RW, Standefer KD, Birch JG et al. An analysis of pelvic asymmetry between different sexes and races in a cadaveric collection. E-poster presented at European Pediatric Orthopedic Society annual meeting, April, 2019.

 

Publications: None to date. Presentations/manuscripts are in preparation addressing:

  • Verification of comparability of 2-dimensional (lateral radiograph) and 3-dimensional (3-D MRI reconstruction) pelvic incidence (PI), and absence of difference between normal subjects/specimens and patients with AIS
  • Presence of lumbosacral vertebral anomalies producing fixed oblique lumbosacral obliquity not detected on plain radiographs in some patients with presumptive AIS (6/60 in this series)
  • Statistically-significant differences between normal subjects/specimens and patients with AIS with respect to innominate and sacral asymmetry, AP translation of the sacrum, and coronal-plane tilt of S1
  • Differences in coronal-plane tilt of the sacrum between AIS patients with or without moderate lumbar deformity, and the relationship of that tilt to radiographic lumbar deformity.
Further Funding:

Further grant obtained as result of POSNA funding: None to date. Project remains internally funded at host institutions (Texas Scottish Rite Hospital for Children and Case Western Reserve University School of Medicine). The project remains intra-institutionally research committee and Institutional Review Board-approved for continued recruitment of normal and AIS volunteers. Based on our findings to date, we believe we have adequate “normal” subject/specimen reconstructions/data. Further recruitment will focus on surgical-grade deformities, with or without substantial lumbar deformities. We will continue to follow patients who have undergone posterior spinal instrumentation and fusion to determine the impact/response of identified lumbosacral deformity on long-term outcome in these patients.