Research Award Details

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A Bioinspired Approach to Large Pediatric Osteochandral Injuries

Grant Recipient: Patrick Whitlock, MD

Co-Investigators: James Lin, PhD
Institution:
Cincinnati Children's Hospital Medical Center
Presentations & Publications:
Presentations:
1.         Gruber, SMS, Ghosh, P, Mueller, KW, Bechtold, T, Whitlock, PW, Lin, CY. Novel Process for 3D Printing with Decellularized Extracellular Matrix for Osteochondral Repair. Poster presented at: Orthopaedic Research Society Annual Meeting; 2018 March IO - 13; New Orleans, LA.
2. Whitlock, P.W., Gruber, S.M.S., Mueller, K.W., Ravishankar, N., Lin, CY., Ghosh, P. Microspheres containing decellularized cartilage induce chondroenesis in vitro and retain functionality after incorporation within a biocompatible polymer filament useful for producing a 3D scaffold. Poster presented at: Orthopaedic Research Society Annual Meeting; 2018 March I 0 - 13; New Orleans, LA.
 
Preliminary Patent Application:
Whitlock et al. Microspheres Containing Decellularized Catiilage Induce Chondrogenesis In Vitro and Remain Functional After Incorporation Within a Poly(Caprolactone) Filament Useful for Fabricating a 3D Scaffold. Provisional US Patent Application# 62/578,037 filed on Oct 27th 2017.
 
Publications:
1.         Ghosh P, Gruber SMS, Lin CY, Whitlock PW. Microspheres containing decellularized cartilage induce chondrogenesis in vitro and remain functional after incorporation within a poly( caprolactone) filament useful for fabricating a 3D scaffold. Biofabrication. 2018;10(2):025007.
2.         Gruber, S.M.S., Ghosh, P., Mueller, K.W., Whitlock, P.W, Lin, C.-Y. Novel Process for 3D printing Decellulai·ized Matrices. Journal of Visualized Experiments. (2018). In press.
 
Further Funding:
None at this time.
Additional Information: