Research Award Details

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A Prospective, International Hip Dysplasia Registry with Follow-up to Skeletal Maturity: an Analysis of Risk Factors, Screening Practices and Treatment Options

Grant Recipient: Kishore Mulpuri, MBBS

Co-Investigators:
Institution:
BC Children's Hospital, Vancouver, Canada
Presentations & Publications:

Presentations:

1. Ellington M, Upasani V, Bomar J, Schaeffer E, Mulpuri K, Sankar W, Mubarak S, IHDI Study Group. Can Brace Treatment be Successful for Dislocated Hips in Infants over Six Months of Age? e-Poster. European Paediatric Orthopaedic Society/Pediatric Orthopaedic Society of North America Annual Meeting, Barcelona, ESP, May 3 -6, 2017. CA.

2. Schaeffer E, Mulpuri K, Sankar W, Upasani V, Clarke N, Herrera J, Kim Y, Foster B, Matheney T, IHDI Study Group. Open Reduction for Developmental Dysplasia of the Hip: Early Outcomes from A Multi-Centre, International Prospective Cohort Study. European Paediatric Orthopaedic Society/Pediatric Orthopaedic Society of North America Annual Meeting, Barcelona, ESP, May 3 -6, 2017. CA.

3. Schaeffer E, Sankar W, Clarke N, Aroojis A, Price C, Mulpuri K, IHDI Study Group. The Need for Further Corrective Surgery in Developmental Dysplasia of the Hip: Surgical Decision-Making and Practice Variability. European Paediatric Orthopaedic Society/Pediatric Orthopaedic Society of North America Annual Meeting, Barcelona, ESP, May 3 -6, 2017. SA.

4. Striano B, Matheney T, Mulpuri K, Price C, Schaeffer E, Upasani V, Williams N, Sankar W, IHDI Study Group. Ultrasound Characteristics of Clinically Dislocated but Reducible Hips in Infantile DDH. e-Poster. European Paediatric Orthopaedic Society/Pediatric Orthopaedic Society of North America Annual Meeting, Barcelona, ESP, May 3 -6, 2017. CA.

5. Paserin O, Quader N, Mulpuri K, Cooper A, Schaeffer E, Hodgson A, Abugharbieh R. Quantifying Dynamic Assessment of Developmental Dysplasia of the Hip. The 2017 International Meeting of Computer Assisted Orthopedic Surgery Society (CAOS), Aachen, Germany, June 14-17, 2017. CA.

6. Schaeffer EK, Mulpuri K, Sankar W, Clarke N, Aroojis A, Price C, IHDI Study Group. The Need for Further Corrective Surgery in Developmental Dysplasia of the Hip: Surgical Decision-Making and Practice Variability. Podium. Canadian Orthopaedic Association Annual Meeting, Ottawa ON, June 15-18 2017. CA.

7. Schaeffer EK, Clarke N, Kelley S, Williams N, Mulpuri K, IHDI Study Group. Femoral Nerve Palsy in Brace Treatment for Developmental Dysplasia of the Hip: Incidence and Outcomes in a Prospective International Cohort. Podium. Canadian Orthopaedic Association Annual Meeting, Ottawa ON, June 15-18 2017. SA.

8. Matheney T , Schaeffer EK, Mulpuri K, Sankar W, Upasani V, Clarke N, Herrera J, Kim Y, Foster B, IHDI Study Group. Open Reduction for Developmental Dysplasia of the Hip: Early Outcomes from A Multi-Centre, International Prospective Cohort Study. Podium. Canadian Orthopaedic Association Annual Meeting, Ottawa ON, June 15-18 2017. CA.

9. Schaeffer EK, Sankar W, Kim H, Kelley S, Cundy P, Price C, Clarke N, Wedge J, Mulpuri K. Inter and Intraobserver Reliability of the Radiographic Diagnosis of Avascular Necrosis of the Femoral Head in Developmental Dysplasia of the Hip. Poster. Canadian Orthopaedic Association Annual Meeting, Ottawa ON, June 15-18 2017. SA. *COA High Scoring Poster

10. Quader N, Hodgson A, Mulpuri K, Cooper A, Abugharbieh R. Tomographic Reconstruction Based Learning for Automatic Characterization of Hip Dysplasia via a 3D Femoral Hip Coverage Feature. Medical Image Computing and Computer Assisted Intervention (MICCAI), Quebec City, QC, Sep 10-14, 2017. CA.

11. Schaeffer EK, Clarke N, Kelley S, Williams N, Mulpuri K, IHDI Study Group . Femoral Nerve Palsy in Brace Treatment for Developmental Dysplasia of the Hip: Incidence and Outcomes in a

 

 

Prospective International Cohort. Pediatric Orthopaedic Society of North America Annual Meeting, Austin Texas, May 9-12, 2018. SA.

12. Schaeffer EK, Sankar WN, Kim HKW, Kelley S, Cundy P, Price CT, Clarke N, Wedge JH, Mulpuri K, IHDI Study Group. Inter- and Intraobserver Reliability of the Radiographic Diagnosis of AVN of the Femoral Head in Developmental Dysplasia of the Hip. Pediatric Orthopaedic Society of North America Annual Meeting, Austin Texas, May 9-12, 2018. SA.

13. Quader N, Schaeffer EK, Mulpuri K, Cooper A, Hodgson A, Abugharbieh R. 3D Ultrasound in the Management of Developmental Dysplasia of the Hip. Pediatric Orthopaedic Society of North America Annual Meeting, Austin Texas, May 9-12, 2018. CA.

14. Quader N, Hodgson A, Mulpuri K, Cooper A, Schaeffer EK, Abugharbieh R. Using 3D Ultrasound to Improve Reliability in Assessing Developmental Dysplasia of the Hip. The 2018 International Meeting of Computer Assisted Orthopedic Surgery Society (CAOS), Beijing-China, June 6-9, 2018. CA.

15. Herrera Soto JA, Schaeffer EK, Mulpuri K, Sankar WN, Williams N, Matheney TH, Upasani VV, IHDI Study Group. The fate of the stubborn hip in bilateral cases where one hip reduces on initial treatment: How many and what to do? Podium. Canadian Orthopaedic Association Annual Meeting, Victoria British Columbia, June 20-23, 2018. CA.

16. Schaeffer EK, Sankar WN, Mulpuri K, IHDI Study Group. Development of a standardized classification system for the diagnosis of Developmental Dysplasia of the Hip in Infants. Poster. Canadian Orthopaedic Association Annual Meeting, Victoria British Columbia, June 20-23, 2018. SA.

17. Schaeffer E, Sankar W, IHDI Group, Mulpuri K. Development of a standardized classification system for the diagnosis of developmental dysplasia of the hip. Société Internationale de Chirurgie Orthopédique et de Traumatologie Orthopaedic World Congress, Montreal, Quebec, Oct 10-13, 2018. SA.

18. Shea K, Burlile J, Taylor I, Mulpuri K, Geng X, Schaeffer E, Habib E, Vagelakos L, Price C. Developmental Dysplasia of the Hip: Care Practices of Orthopaedic Surgeons in North America. American Academy of Orthopaedic Surgeons Annual Meeting, Las Vegas, Nevada, Mar 12-16, 2019. CA.

19. Shea K, Burlile J, Taylor I, Mulpuri K, Geng X, Schaeffer E, Habib E, Vagelakos L, Price C. Developmental Dysplasia of the Hip: Care Practices of Orthopaedic Surgeons in North America. Poster. Pediatric Orthopaedic Society of North America Meeting, Charlotte, North Carolina, May 15-18, 2019. CA.

20. Schaeffer E, Bone J, Sankar W, Matheney R, IHDI Study Group, Mulpuri K. Predictors of Avascular Necrosis of the Femoral Head Following Closed or Open Reduction in the Treatment of Developmental Dysplasia of the Hip. Podium. Pediatric Orthopaedic Society of North America Meeting, Charlotte, North Carolina, May 15-18, 2019. SA.

21. Herrera-Soto J, Schaeffer E, Mulpuri K, Sankar W, Williams N, Matheney T, Upasani V, IHDI Study Group. The Fate of the Stubborn Hip in Bilateral Cases Where One Hip Reduces on Initial Treatment: How Many and What to Do? Poster. Pediatric Orthopaedic Society of North America Meeting, Charlotte, North Carolina, May 15-18, 2019. CA.

22. Pandey P, Quader N, Mulpuri K, Guy P, Garbi R, Hodgson A. Shadow Peak: Accurate Real-time Bone Segmentation for Ultrasound and Developmental Dysplasia of the Hip. 19th Annual Meeting of the International Society for Computer Assisted Orthopaedic Surgery, New York, New York, Jun 19-

 

 

22, 2019. CA.

23. Schaeffer E, Aroojis A, Shah H, Krishnamoorthy V, Patwardhan S, Sahu C, IHDI Study Group, Mulpuri K. The Importance of Globalization in Prospective Study Groups: Increasing the Relevance of Research on Developmental Dysplasia of the Hip to a Global Patient Population. Poster. International Combined Orthopaedic Research Societies/Canadian Orthopaedic Association Annual Meeting, Montreal, Quebec, Jun 19-22, 2019. SA. *COA High Scoring Poster

24. Paserin O, Garbi R, Hodgson A, Cooper A, Mulpuri K. Automatic Evaluation of 3D Femoral Head Coverage Variability for Dynamic Assessment of Hip Dysplasia. Podium. International Combined Orthopaedic Research Societies/Canadian Orthopaedic Association Annual Meeting, Montreal, Quebec, Jun 19-22, 2019. SA.

25. Schaeffer E, Bone J, Sankar W, Matheney T, IHDI Study Group, Mulpuri K. Predictors of Avascular Necrosis of the Femoral Head Following Closed or Open Reduction in the Treatment of Developmental Dysplasia of the Hip. Podium. International Combined Orthopaedic Research Societies/Canadian Orthopaedic Association Annual Meeting, Montreal, Quebec, Jun 19-22, 2019. SA.

26. Yamini R, Schaeffer E, Bajno L, Krishnaswamy W, Randhawa M, Mulpuri K. Multidisciplinary Clinic for Developmental Dysplasia of the Hip. Podium. International Combined Orthopaedic Research Societies/Canadian Orthopaedic Association Annual Meeting, Montreal, Quebec, Jun 19-22, 2019. SA.

 

Publications:

Published

1. Paserin O, Quader N, Mulpuri K, Cooper A, Schaeffer E, Hodgson A, Abugharbieh R. Quantifying dynamic assessment of developmental dysplasia of the hip. EPiC Series in Health Sciences, EasyChair. 2017; 1: 224-227. CA (contributed data acquisition, data analysis, and manuscript preparation).

2. Quader N, Hodgson A, Mulpuri K, Schaeffer EK, Abugharbieh R. Automatic evaluation of scan adequacy and dysplasia metrics in 2D ultrasound images of the neonatal hip. Ultrasound Med Biol. 2017; 43(6):1252-1262. DOI: 10.1016/j.ultrasmedbio.2017.01.012. CA (contributed data acquisition, data analysis, and manuscript preparation). Impact Factor 2.205. Cited by 9.

3. Walton S, Schaeffer E, Mulpuri K, Cundy P, Williams N. Evaluating the role of prereduction hip traction in the management of infants and children with developmental dysplasia of the hip (DDH): protocol for a systematic review and planned meta-analysis. BMJ Open. 2018 Jan; 8(1): e019599. CA (contributed protocol development and manuscript preparation). Impact Factor 2.376. Cited by 2.

4. Quader N, Hodgson A, Mulpuri K, Cooper A, Schaeffer E, Abugharbieh R. Using 3D Ultrasound to Improve Reliability in Assessing Developmental Dysplasia of the Hip. EasyChair. 2018; 1: 175-178. CA (contributed data acquisition, data analysis, and manuscript preparation).

5. Schaeffer EK, Mulpuri K. Developmental dysplasia of the hip: addressing evidence gaps with a multicentre prospective international study. The Medical Journal of Australia. 2018 May;208(8):359-64. SA. Impact Factor 5.332. Cited by 7.

6. Quader N, Schaeffer EK, Hodgson AK, Abugharbieh R, Mulpuri K. A systematic review and meta-analysis on the reproducibility of ultrasound-based metrics for assessing developmental dysplasia of the hip. J Pediatr Orthop. 2018 Jul;38(6):e305-e311. SA. Impact Factor 2.046. Cited by 2.

7. Aarvold A, Schaeffer EK, Kelley S, Clarke NMP, Herrera-Soto JA, Price CT, Mulpuri K, IHDI Study Group. Management of irreducible hip dislocations in infants with developmental dysplasia of the hip

 

 

diagnosed below 6 months of age. J Pediatr Orthop. 2018 Jan; 39(1): e39-e43. SA. Impact Factor 2.046. Cited by 1.

8. Schaeffer EK, Lubicky J, Mulpuri K. AAOS Appropriate Use Criteria: The management of developmental dysplasia of the hip in infants up to 6 months of age: Intended for use by general pediatricians and referring physicians. J Am Acad Orthop Surg. 2018 Apr 15; 27(8): e365-e368. SA. Impact Factor 2.348

9. Sankar WN, Gornitzky AL, Clarke NM, Herrera-Soto JA, Kelley SP, Matheney T, Mulpuri K, Schaeffer EK, Upasani VV, Williams N, Price CT. Closed reduction for developmental dysplasia of the hip: early-term results from a prospective, multicenter cohort. J Pediatr Orthop. 2019 Mar 1;39(3):111-8. CA. Impact Factor 2.046. Cited by 9.

10. Schaeffer E, Lubicky J, Mulpuri K. AAOS Appropriate Use Criteria: The Management of Developmental Dysplasia of the Hip in Infants up to Six Months of Age: Intended for Use by Orthopaedic Specialists. J Am Acad Orthop Surg. 2019 Apr 15; 27(8): e369-e372. SA. Impact Factor 2.398.

 

Submitted/ In Progress

1. Schaeffer EK, Price CT, Mulpuri K, IHDI Study Group. Developmental Dysplasia of the Hip and laterality: The importance of graded severity of the contralateral hip. Submitted to Journal of Pediatric Orthopaedics June 2019.

2. Mulpuri K, Mubarak S, Matheney T, Kelley S, Castaneda P, Foster B, Clarke N, Price C. Prospective observational cohort study of children with hips dislocated at rest. Recruitment in progress.

3. Mulpuri K, Abugharbieh R, Hodgson AJ, Quader N. Automatic characterization of the neonatal hip using ultrasound imaging. Manuscript in progress.

4. Schaeffer EK, Pathy R, Mulpuri K. Do infants with risk factors for developmental dysplasia of the hip require further radiographic follow-up after a normal clinical examination and ultrasound? A retrospective chart review. Data collection in progress.

Further Funding:

Further grant obtained as result of POSNA funding:

1. Samson Award from the Canadian Orthopaedic Foundation, 2018

2. Research Grant from the Centre for International Child Health, 2019

Additional Information: