Research Award Details

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Comparative mechanobiological Response of Growth Plate Explants under Static and Dynamic Loading

Grant Recipient: Isabelle Villemure, P.Eng, PhD

Co-Investigators: Stefan Parent, MD, PhD
Institution:
Research Ctr-CHU Sainte-Justine, Montreal
Presentations & Publications:
Presentations: D: Sergerie K, Beauchemin P-F, Moldovan, F Parent, S, Villemure I. Response of Growth Plate Explants under Static and Dynamic Loading : A Histomorphological Study. The International Research Society of Spinal Deformities (IRSSD). July 1-3 2010, Montréal, Canada. (Podium) I: Valteau B, Grimard G, Londono I, Moldovan F, Villemure I. In Vivo dynamic bone growth modulation is less detrimental but as effective as static growth modulation. 17th Annual Canadian Connective Tissue Conference (CCTC). École Polytechnique, Montreal, Canada, May 27-29, 2011. (E-Poster) I: Valteau B, Grimard G, Londono I, Moldovan F, Villemure I. In vivo effects of static versus dynamic compression on the growth rate and on the growth plate histomorphometry. 40th Annu Annual Meeting of the Société de Scoliose du Québec (SSQ).October 28-30 2010, Burlington VT, USA (Podium; 2nd Prize Roger Simoneau in Fundamental Research ) Publications: D: Sergerie K, Parent S, Londono I, Moldovan F, Villemure I. Growth plate explants respond differently to in vitro static and dynamic loadings. J Orthop Res. 2011 Apr; 29(4):473-480. I: Valteau B, Grimard G, Londono I, Moldovan F, Villemure I. In vivo dynamic bone growth modulation is less detrimental but as effective as static growth modulation. Bone 2011 Nov; 49(5): 996-1004.
Further Funding:
1. NSERC - Discovery Grant (2009-2014); Effects of mechanical loading on bone growth: an in vivo mechanobiological study. 2. NSERC - Discovery Grant (2014-2019): Biomechanical and microstructural evaluation of newly formed bone following static/dynamic bone growth modulation in an immature animal model. 3. Patent: Aubin CÉ, Parent S, Driscoll M., Villemure I, Moldovan F. CYCLIC CONTROLLED DYNAMIC DEVICE FOR THE CORRECTION OF SPINAL DEFORMITIES. United States Patent and Trademark Office; EFS-ID: 15034506 (Feb 25 2013).
Additional Information: