Research Award Details

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Cell Enhanced Hybrid Hydrogel Scaffolds for Tissue Engineering to Regenerate a Native Physis

Grant Recipient: Todd Milbrantdt, MD

Co-Investigators: David Puelo, PhD
Kentucky Clinic, Lexington
Presentations & Publications:
Presentations: 1. Clark, A., Milbrandt, T.M., Hilt, J.Z., and Puleo, D.A. (2013). Sustained release from protein-loaded biodegradable polymeric scaffolds for growth plate regeneration. Presented at the 40th Annual Meeting & Exposition of the Controlled Release Society, July 21-24, Honolulu, HI. 2. Clark, A., Puleo, D., Hilt Z., Milbrandt, T. “The Effect of Adding a Hydrogel Porogen into a Poly(lactic-co-glycolic acid) Scaffold”. Poster presented at the Society For Biomaterials Annual Meeting, April 2013. AWARD WINNER Publications: 1. Hawkins, A.M., Tolbert, M.E., Newton, B., Milbrandt, T.A., Puleo, D.A., and Hilt, J.Z. (2013). Tuning biodegradable hydrogel properties via synthesis procedure, Polymer 54: 4422-4426. 2. Hawkins, A.M., Milbrandt, T.A., Puleo, D.A., and Hilt, J.Z. (2014). Composite hydrogel scaffolds with controlled pore opening via biodegradable hydrogel porogen degradation, J. Biomed. Mater. Res. Part A 102:400-12. 3. Clark, A., Hilt, J., Milbrandt, T.A., Puleo, D. “Retention of Insulin-Like Growth Factor 1 Bioactivity During Fabrication of Sintered Polymeric Scaffolds”. Biomed. Mater – BMM/490658/PAP/156174, 2014. 4. Clark, A., Milbrandt, T.A., Hilt, J.Z., Puleo, D.A., “Mechanical Properities and Dual Drug Delivery Application of Poly(Lactic-Co-Glycolic Acid) Scaffolds Fabricated with a Poly(β-Amino Ester) Porogen”. Acta Biomater., 2014 Jan 12, pii: S1724-7061(14)00011-7. DOI: 10.1016/j.actbio.2013.12.061. [Epub ahead of print] PubMed PMID: 24424269. 5. Clark, A., Milbrandt, T.A., Hiltz, J.Z., Puleo, D.A., “Tailoring Properties of Microsphere-Based Poly(Lactic-Glycolic Acid) Scaffolds”. J. Biomed Mater Res A. 2014 Feb; 102(2): 348-57. DOI: 10.1002/JBM.A,34706. Epub 2013 May 14. PubMed PMID: 23533090.
Further Funding:
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