Research Award Details

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Natural History and Outcomes of Pediatric Orthopaedic Conditions

Grant Recipient: Stuart L Weinstein, MD

Co-Investigators:
Institution:
Univ of Iowa College of Medicine
Presentations & Publications:
Publications: 1. Farsetti P, Weinstein SL, Ponseti IV: The Long Term Follow-up and Radiographic Outcome of Untreated and Non-Surgically Treated Metatarsus Adductus. Journal of Bone and Joint Surgery 76A: 257-265, 1994. 2. Samani D, Weinstein SL: The Pelvic Tear Figure: Three Dimensional Anatomy and its Effect on Rotation. Journal of Pediatric Orthopaedics 14:650-659, 1994. 3. Morcuende JA, Weinstein SL, Dietz FR, Ponseti IV: Plaster Cast Treatment of the Clubfoot: The Ponseti Method of Manipulation and Casting. Journal of Pediatric Orthopaedics, Part B 3:161-167, 1994. 4. Malvitz T, Weinstein SL: Congenital Hip Dysplasia: Review of 152 Closed Reductions with 31 Year Follow-up. Journal of Bone and Joint Surgery 76A: 1777-1792, December 1994. 5. Albinana J, Morcuende JA, Weinstein SL: Radiologic Pelvic Asymmetry in Unilateral Late Diagnosed Developmental Dysplasia of the Hip. Journal of Pediatric Orthopaedics 15:753-762, November-December 1995. 6. Maxian TA, Brown TD, Weinstein SL: Chronic Stress Tolerance Levels for Human Articular Cartilage: Two Non-Uniform Contact Models Applied to Long Term Follow-up of CDH. Journal of Biomechanics 28:159-166, 1995. 7. Carney B, Weinstein SL: The Natural History of Untreated Slipped Capital Femoral Epiphysis. Clinical Orthopaedics and Related Research 322:43-47, 1996. 8. Noonan KJ, Weinstein SL, Jacobson WC, Dolan LA: Milwaukee Bracing in Patients with Progressive Idiopathic Scoliosis. Journal of Bone and Joint Surgery 78A: 557-567, 1996. 9. Manor DA, Weinstein SL, Dietz FR: Long Term Follow-up of Chiari Osteotomy in Myelomeningocele. Journal of Pediatric Orthopaedics 16:769-773, 1996. 10. Albinana J, Morcuende JA, Weinstein SL: The Tear Drop in Congenital Dislocation of the Hip Diagnosed Late. Journal of Bone and Joint Surgery 78A: 1048-1055, 1996. 11. Morcuende JA, Meyer MD, Dolan LA, Weinstein SL: Long Term Outcome After Open Reduction Through an Anteromedial Approach in Congenital Dislocation of the Hip. Journal of Bone and Joint Surgery 79A: 810-817, 1997. 12. Weinstein SL, Carney BT: Slipped Capital Femoral Epiphysis: Pediatric Master Class. Current Orthopaedics 11:51-56, 1997. 13. Noonan KJ, Dolan LA, Jacobson WC, Weinstein SL: Long Term Psychologic Characteristics of Patients Treated for Idiopathic Scoliosis. Journal of Pediatric Orthopaedics 17:712-717, 1997. 14. Neyt JG, Weinstein SL, Dolan LA: et. al. Stulberg Classification System for Evaluation of Legg-Calve-Perthes Disease: Intra and Inter-rater Reliability. Journal of Bone and Joint Surgery 81A: 1209-1216, September 1999. 15. Weinstein SL: 12th Annual Bristol-Myers-Squibb/Zimmer Award for Distinguished Achievement in Orthopaedic Research: Long Term Follow-up of Pediatric Orthopaedic Conditions; Natural History and Outcomes of Treatment. Journal of Bone and Joint Surgery 82A: 980-990, July 2000. 16. Kim HW, Morcuende JA, Dolan LA, Weinstein SL: Acetabular Development in Developmental Dysplasia of the Hip Complicated by Lateral Growth Disturbance of the Capital Femoral Epiphysis. Journal of Bone and Joint Surgery 82A: 1692-1700, December 2000. 17. Weinstein SL: Quality of life and back pain: outcome 16.7 years after Harrington instrumentation. Point of View; Spine: Jul; 27(13): 1463-4, 2002. 18. Kim HW, Weinstein SL: Congenital Pseudoarthrosis of the Tibia. Clin. Orthop. Rel Res: 405:250-257, 2002. 19. Schultz WR. Weinstein JN, Weinstein SL, Smith BG: Prophylactic Pinning of the Contralateral Hip in Slipped Capital Femoral Epiphysis. Evaluation of Long-Term Outcome for the Contralateral Hip with the Use of Decision Analysis. J. Bone and Joint Surg. 84A: 1305-1314, 2002. 20. Dobbs MB, Lenke KG, Szymanski DA, Morcuende JA, Weinstein SL, Bridwell KH, and Sponseller PD: Prevalence of Neural Axis Abnormalities in Patients with Infantile Idiopathic Scoliosis. J. Bone and Joint Surg. 84A: 2230-2234, December 2002. 21. Weinstein SL, Dolan LA, Spratt KF, Peterson KK, Spoonamore MJ, Ponseti IV: Health and Function of Patients with Untreated Idiopathic Scoliosis. A 50-Year Natural History Study. JAMA 289: 559-567, February 5, 2003. 22. Donnelly, MJ, Dolan LA, Weinstein SL: How Effective is Bracing for Treatment of Scoliosis? American Family Medicine; Jan 1; 67(1): 32, 2003. 23. Farsetti, P; Weinstein SL; Caterini R; De Maio F, Ippolito E: Sprengel’s Deformity: Long term follow-up study of 22 Cases. J. Pediatric Orthopaedics B:12:202-210, May 2003. 24. Morcuende JA, Minhas, R; Dolan LA, Stevens J; Beck J; Wang K; Weinstein SL and Sheffield V: Allelic Variants of Human Melatonin 1A Receptor in Patients with Familial Adolescent Idiopathic Scoliosis. Spine 28: 2005-2029, 2003. 25. Sabesan V, Dolan LA, Weinstein SL: Point of View, The Objective Measurement of Spinal Orthosis Use for the Treatment of Adolescent Idiopathic Scoliosis, Nicholson GP, Ferguson-Pell Smith K, Edgar M and Morley T: Spine 28:2250-2251, 2003. 26. Pedersen D, Lamb CA, Dolan LA, Morcuende JA, Weinstein SL: Radiographic measurements in DDH: Reliability and validity of a digitizing program. Journal of Pediatric Orthopaedics 24:156-160, 2004 27. Pedersen D, Lamb CA, Dolan LA, Morcuende JA, Weinstein SL: Radiographic measurements in DDH: Reliability and validity of a digitizing program. Journal of Pediatric Orthopaedics 24:156-160, 2004 28. Spoonamore MJ; Dolan LA; Weinstein, SL. Use of the Rosenberger Brace in the Treatment of Progressive Adolescent Idiopathic Scoliosis. Spine 29:1458-1464, 2004 29. Albiñana J; Weinstein SL; Morcuende JA; Dolan LA; Meyer, MD: DDH- Acetabular dysplasia after treatment for developmental dysplasia of the hip: Evidence-based prediction rules with implications for secondary procedures. The Journal of Bone and Joint Surgery British Volume, 86B: 876-886146. 30. Donnelly MJ, Dolan LA, Grande L, Weinstein SL: Patient and Parent Perspectives on Treatment for Adolescent Idiopathic Scoliosis. Iowa Orthopaedic Journal, 24:76: The Iowa Orthopedic Journal 25:xx-xxiii, 2005 31. Fernandes P and Weinstein SL: Natural History of Early Onset Scoliosis: Journal of Bone and Joint Surgery 89A: Supplement 1: 21-33, 2007 32. Dolan LA, Donnelly MJ, Spratt KF, and Weinstein SL: Professional Opinion Concerning the Effectiveness of Bracing Relative to Observation in Adolescent Idiopathic Scoliosis. Journal of Pediatric Orthopaedics Volume 27:270-276, April May 2007 33. De Maio F, Dolan LA, De Luna V, Weinstein SL: Posterior Spine Fusion with Moss Miami Instrumentation for Adolescent Idiopathic Scoliosis: Radiographic, Clinical and Patient Centered Outcomes. The Iowa Orthopaedic Journal: 27:28-39, 2007 34. Boos N, Dolan LA, Weinstein SL: Long Term Clinical and Radiographic Results of Cotrel-Dubousset Instrumentation of Right Thoracic Adolescent Idiopathic Scoliosis. The Iowa Orthopedic Journal: 27: 40-46 2007 35. Dolan LA and Weinstein SL: Surgical Rates after Observation and Bracing for Adolescent Idiopathic Scoliosis: An Evidence Based Review. Spine: 32: (19 Suppl): 91-100, 2007 36. Fernandez CA, Dolan LA, Weinstein SL, Morcuende JA: Natural History of Type III Growth Disturbance after Treatment of Developmental Dislocation of the Hip. Iowa Orthopaedic Journal 28:27-35, 2008 37. Peterlein CD, Schofer M, Tibesku CO, Weinstein SL, Fuchs-Winkelman S: Evaluation of the Ipsilateral Knee more than 40 years after successful closed reduction of DDH. J Child Orthop 2: 251-254, 2008 38. Campos MA, Fernandes P, Dolan LA and Weinstein SL: Infantile Thoracolumbar Kyphosis Secondary to Lumbar Hypoplasia. Journal of Bone and Joint Surgery, 90A: 1726-1729, 2008 39. Weinstein SL, Dolan LA, Morcuende JA, Cheng JCY, Danielsson, A: Adolescent Idiopathic Scoliosis. Lancet 371:1527-1537, May 3-9, 2008 40. Dolan LA, Sabesan V, Weinstein SL and Spratt KF: Preference Assessment of Recruitment into a Randomized Trial for Adolescent Idiopathic Scoliosis; Journal of Bone and Joint Surgery 90: 2594-2605, December 2008 41. Albert GW; Hansen DR; Menezes AH; Greenlee JDW, Weinstein SL: “Chiari Type I Malformation in Children Below the Age of 6 Years: Presentation and Surgical Outcome”. J Neurosurg Pediatrics 5:554-561, 2010 42. Mendoza-Lates S, Ries Z, Gao Y, Weinstein SL: Natural History of Spinopelvic Alignment Differs from Symptomatic Deformity of the Spine. Spine 35:16; E792-E798, 2010 43. Campos M, Dolan L, Weinstein SL: Unanticipated Revision Surgery in Adolescent Idiopathic Scoliosis. Spine37:1048-1053, 2012 44. Weinstein SL, Dolan LA, Wright JG, Dobbs MB; Design of the Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST). Spine 38(21):1832-1841, October 01, 2013 45. Weinstein SL, Dolan LA, Wright JG, Dobbs MB; Effects of Bracing in Adolescents with Idiopathic Scoliosis N Engl J Med 2013; 369:1512-1521 46. Ahmed R, Mahaney K, Awe OO, Torner JC, Weinstein S, and Menezes AH: Long Term Incidence and Risk Factors for Development of Spinal Deformity Following Surgical Resection of Pediatric Intramedullary Tumors. Journal of Neurosurgery (Accepted for Publication) 2013 47. Herickhoff PK, O'Brien MK, Dolan LA, Morcuende JA, Peterson JB, Weinstein SL.: The gothic arch: a reliable measurement for developmental dysplasia of the hip. Iowa Orthop J. 2013;33:1-6 48. Dolan LA, Wright JG, Weinstein SL: Effects of Bracing in Adolescent Idiopathic Scoliosis. Response of Letter to the Editor; N Engl J Med 2013, 370. 680-681 49. Mendoza-Lattes S, Besomi, J, O’Sullivan C, Ries Z, Gnanapradeep G, Nash R, Gao Y, Weinstein SL:: Pediatric Spine Trauma in the United States – HCUP KID’s Analysis, 1997 -2009 (Submitted for Publication)
Further Funding:
1. Adolescent Idiopathic Scoliosis - Natural History of Untreated Patients, Stuart L. Weinstein, M.D., Principle Investigator. Orthopaedic Research and Education Foundation (OREF) 1991-1993, $64,000.00 2. Physical Validation of Contact Stress Model Predictions in Developmental Dysplasia of the Hip, Stuart L. Weinstein, M.D. Principle Investigator, Thomas D. Brown, PhD. Co Principle Investigator, Children’s Miracle Network Telethon 1993-1994, $6890.00 3. 40-Year Follow Up Study of Developmental Dysplasia of the Hip, Stuart L. Weinstein, M.D. Principle Investigator, Thomas D. Brown, PhD, and Lori A. Dolan, RN Co-Principle Investigators, Children’s Miracle Network Telethon 1996-1997, $7500.00 4. Prediction of Osteoarthritis Based on Articular Surface Morphology at 40 year Follow Up of Congenital Hip Dysplasia, Stuart L. Weinstein, M.D. Principle Investigator, Tom Brown, Co-PI Central Fund for Research Enhancement, University of Iowa, $8100.00 5. Nonlinear Computational Biomechanics of the Hip Thomas D Brown, PhD, Principle Investigator; Stuart L. Weinstein, M.D., Clinical Co Investigator. National Institute of Arthritis and Musculoskeletal and Skin Disease; National Institute of Health $2.58 Million 11/99-10/04 6. The Use of TLSO's in the Treatment of Adolescent Idiopathic Scoliosis: A Prospective Randomized, Controlled Study. Stuart Weinstein, MD Principle Investigator, Children’s Miracle Network Grant $7500 7. DePuy Motec Unrestricted Educational Grant for Spine Related Research. Stuart Weinstein, MD, Principle Investigator 8. The Whitaker Foundation: Chronic Stress Tolerance of Human Articular Cartilage: Developmental Hip Dysplasia of the Hip as a Model of Long Term Overloading, Douglas Pederson, PhD Principle investigator; Stuart L. Weinstein, MD consultant, $219,561 9. Bracing in Adolescent Idiopathic Scoliosis (BrAIST); Stuart L. Weinstein, MD, Principle Investigator; US Department of Public Health and Human Services-National Institutes of Health (1R21 AR49687-01) $135,250.00 9/02-5/03 10. Bracing in Adolescent Idiopathic Scoliosis (BrAIST); Stuart L. Weinstein, MD, Principle Investigator; US Department of Public Health and Human Services-National Institutes of Health 1 RO1 AR052113-01 $4,907,288; 2006-2011. Additional Funding ($1,900,000) through CIHR (Canada) and Shriners Hospitals 11. Bracing in Adolescent Idiopathic Scoliosis (BrAIST); Stuart L. Weinstein, MD, Principle Investigator; US Department of Public Health and Human Services-National Institutes of Health 2R01AR052113-06 $695,755; 9/1/2012-8/31/2013 12. Bracing in Adolescent Idiopathic Scoliosis (BrAIST); Stuart L. Weinstein, MD, Principle Investigator; US Department of Public Health and Human Services-National Institutes of Health 2R01AR052113-06 $104,000; 9/1/2013-8/31/2014 13. BrAIST II Study Group (B2SG); OREF Scientific Forum/Spine Care Grant; $35,825.00, July 1, 2011 14. Bracing in Adolescent Idiopathic Scoliosis II (BrAIST II) Ira and Libbie Pink Charitable Foundation, $175,000, 2012-2017
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