Research Award Details

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Fiber Optic Detection of Spinal Ischemia During Vertebral Column Distraction

Grant Recipient: James Barsi, MD

Co-Investigators: Thomas Floyd, MD
Institution:
Res. Fdn. State Univ. of NY at Stony Brook
Presentations & Publications:
Further Funding:
NIH U01NS095761 09/01/2016 – 08/31/2021,   $800,000
Spinal Fiber Optic Monitoring
Aim 1) To design and produce a second generation multi-level spinal cord fiber-optic probe, capable of axially discriminating ischemic disturbances across multiple vertebral regions in the spinal cord.
Aim 2) To continue to develop and optimize a real-time fiber optic monitoring platform for the monitoring of spinal cord blood flow and oxygenation.
Aim 3) To conduct preliminary bench and pre-clinical testing of the second generation multi-level probes and PXI-platform real-time monitor.
Aim 4) To design and produce a compact, portable, user friendly, DCS/DOS monitor, capable of being used at the bedside.
Aim 5) To complete bench and pre-clinical testing of the second generation probes and monitor.
 
 
Additional Information:
Study Aims: To determine if spinal cord ischemia secondary to spine distraction can be detected by the DCS fiber optic device prior to detection by electrophysiological changes.
 
Research Findings: A fiber optic DCS probe utilizing DCS detects spinal cord ischemia at a mean of 14.6±9.5 mm.  The ischemic event occurred 4.5 minutes before electrodiagnostic changes.